Bros, I would go up to 500 mg. That's all you need. I've seen some people run 750 or 1,000 mg. You can try it but I don't think the results are worth the side effects.
Bros, the problem with S4 is that if you're going to use it, you're going to get side effects. If you're not using it at a high enough dosage, you're not going to get side effects and you're not going to get the best results.